CHE 524 - Magnetic Resonance

This course provides an introduction to the fundamental quantum mechanics of the magnetism of spin-1/2 (and higher) particles. It includes a study of the Bloch equations (the responses of the magnetism to continuous-wave and pulsed irradiation) and a discussion of the experimental hardware and techniques commonly employed. Topics covered include the basics of the spin Hamiltonian (chemical shifts, J, dipolar, and quadrupolar couplings), dynamics and relaxation 1-D spectroscopy (spin and chemical exchange, lineshapes, spin echos, etc.), 2-D spectroscopy (homonuclear and heteronuclear correlation), techniques for studies of solids and liquid crystals (magic angle spinning, cross polarization, quadrupolar echo), and the principles of magnetic resonance imaging. Applications to the biological and material sciences, as well as chemical problems, will be discussed.

3 credits

Grading Letter graded (A, A-, B+, etc.)

Offered Spring alternate years